*Corresponding Author : Tarik Hanafi
Department of Dermatology, Mohammed V Military Hospital, Mohammed V University of Rabat, Rabat, Morocco.
Email: [email protected]
Received : Jul 19, 2024
Accepted : Aug 07, 2024
Published : Aug 14, 2024
Archived : www.jcimcr.org
Copyright : © Hanafi T (2024).
Sarcoidosis is a systemic granulomatosis, characterized by the presence of epithelioid and gigantocellular granulomas without necrosis. Lipoid necrobiosis is a cutaneous granulomatosis, closely linked to diabetes, associating palisade granulomas and foci of necrobiosis. We report a case of cutaneous sacricoidosis with the type of lipoid necrobiosis.
ntidiabetic Drugs (OADs) and for moderate obesity with BMI of 27.1. She consulted for erythemato-atrophic patches on the legs, which had been present for 6 months. Dermatological examination found multiple finely scaly oval erythematous plaques, well defined, with a sclero-atrophic center and an indurated annular border located bilaterally and asymmetrically in the pre-tibial region of both legs (Figure 1). The remainder of the physical examination was unremarkable. Histological examination of skin biopsy showed a well-differentiated squamous coating supported by a fibrous dermis, seat of inflammatory and granulomatous epithelial-giganto-cellular changes, forming palisades around necrobiotic eosinophilic material without vascular or nervous involvement, orienting towards pseudo-necrobiotic sarcoidosis. As part of the sarcoidosis lesion assessment, a chest CT scan revealed stage 2 mediastino-pulmonary involvement. The patient was put on synthetic antimalarials and topical corticosteroids under occlusion with partial improvement.