Birt-Hogg-Dubé Syndrome (BHDS) is a rare autosomal dominant disorder characterized by pulmonary cysts, recurrent pneumothorax, skin lesions, and renal tumors. We report three cases of pneumothorax caused by BHDS that were treated with bullectomy followed by Skipped Pleural Covering (SPC) Using Polyglycolic Acid (PGA) sheets.
Volume-6, 2025
Issue 7 (July)
Coronary artery fistulae are rare vascular anomalies with a wide spectrum of clinical presentations. We report the case of a 55-year-old male with a large coronary artery to pulmonary artery fistula, identified following evaluation for exertional breathlessness.
Crohn’s Disease (CD) and Intestinal Tuberculosis (ITB) have similar clinical, endoscopic, and histopathological characteristics and possess a significant diagnostic challenge in tuberculosis-endemic regions. Misdiagnosis can lead to delayed treatment or use of inappropriate immunosuppressive therapy.
Gastric signet-ring cell carcinoma (SRCC) is an aggressive histological subtype of gastric cancer that frequently presents with atypical symptoms. Lymphedema as the initial manifestation is exceptionally uncommon.
Double pylorus is a rare endoscopic finding, often secondary to chronic peptic ulcer disease and mucosal fistulization. It may become evident incidentally or during an investigation of upper gastrointestinal (GI) bleeding. Our case was a hemodynamically unstable woman who presented with hematemesis.
Concomitant herpes simplex virus 2 (HSV-2) genitalis and meningitis is an uncommon presentation. In this case, a female patient in her twenties, with a recent history of herpes genitalis (HSV-2) lesions, presented with fever, headache, neck pain, and photosensitivity. Complete Blood Count (CBC).
Slipping Rib Syndrome (SRS) is a rare medical condition often misdiagnosed due to limited awareness in the medical field. This particular case study showcases an unusual presentation of SRS with gastrointestinal symptoms. SRS occurs when the false ribs have unstable connections.
Mauriac Syndrome (MS) is a rare complication of poorly controlled type 1 diabetes, primarily affecting children and adolescents, with fewer cases reported in adults. It is characterized by delayed growth, delayed puberty, hepatomegaly, and liver dysfunction, resulting from glycogen accumulation in the liver due to diabetic imbalance.
We report a rare case of massive purulent pericarditis with cardiac tamponade in a 19-year-old immunocompetent patient, diagnosed using portable Point-of-Care Ultrasound (PoCUS). The ultrasound revealed a swinging heart, right ventricular collapse, and a large pericardial effusion with a positive plankton sign-features consistent with purulent pericarditis.
We report the case of a 54-year-old man with a surgical history of sigmoidectomy and colorectal anastomosis performed ten years prior for sigmoid volvulus. The postoperative course was marked by persistent abdominal bloating, requiring repeated colonic exsufflation.
Gray zone lymphoma (GZL) is a rare hematologic malignancy with overlapping features of diffuse large B-cell lymphoma (DLBCL) and classical Hodgkin lymphoma (cHL). It typically involves the mediastinum and shows variable clinical behavior, complicating diagnosis and management.
Epidermoid cysts, also known as a sebaceous cyst, are en-encapsulated subepidermal nodules filled with keratin. These cysts can manifest anywhere in the body, including rare occurrences in the perineal region.
Deep cerebral venous thrombosis (DCVT) is an infrequent subtype of cerebral venous thrombosis (CVT), often presenting with nonspecific neurological symptoms. Its imaging hallmark—bilateral thalamic involvement—necessitates rapid recognition to guide prompt anticoagulation.
Intraosseous hemangiomas are benign vascular tumors which are more commonly seen in the vertebrae and skull but they rare in the ribs [1]. Rib hemangiomas can mimic malignant rib lesions and definitive clinical and imaging diagnosis might be difficult and pathological confirmation will be required.
In modern society, the sub-health state (SHS) is becoming increasingly apparent as a result of rapid work, study, and interpersonal relationships. As a state between health and disease, it usually occurs due to long-term unhealthy habits, such as staying late, anxiety, tension, and so on.
Stage 3 liver trauma (S3PLT), characterized by parenchymal injury as well as possible vessel involvement, provides a unique challenge in trauma management. Our paper discusses the case of a 59-year- old undercover police officer who suffered a stab wound to the right upper abdomen, resulting in S3PLT.
Double cortex syndrome is a rare X-linked dominant disorder affecting females. It typically presents with developmental delay and epileptic seizures. Brain MRI features are characteristic and strongly suggestive of the diagnosis.
A 60-year-old male presented with a 1-month history of ocular photosensitivity, pruritus, infraorbital swelling, and acute binocular vision loss. He was admitted for evaluation of anterior optic neuropathy and temporal arteritis.
A previous cesarean section case has a potential risk of uterine rupture at the primary cesarean scar site. Uterine rupture at sites like fundus and posterior wall with intact previous cesarean scar are rare events and both are associated with high fetomaternal morbidity and mortality.
Primary Cardiac Angiosarcoma (PCA) is rare. Clinical signs are not specific. 40 years old female was diagnosed of PCA with multiple metastasis, inoperable case. Palliatively treated with chemo and immunotherapy, later radiation therapy for metastasis. Was admitted to the hospital with chest pain.
Lafora Disease (LD) is a rare autosomal recessive glycogen storage disorder characterized by Progressive Myoclonic Epilepsy (PME) and neurodegeneration, typically manifesting in adolescence. We aim to evaluate the potential efficacy of Cannabidiol (CBD) in managing seizures and cognitive symptoms in Lafora disease.
A 54-year old female presented to an outpatient primary care clinic with a one month history of recurrent, high fevers. A complete review of systems was negative. The patient underwent a thorough infectious work-up and well as imaging to evaluate for possible malignancy. All of this testing was normal.
Schwannomas are uncommon benign tumors of Schwann cell origin, most often encountered in the head, neck, and extremities—yet their appearance in the colon is a medical rarity. We report the case of a 61-year-old woman whose year-long history of vague abdominal pain, postprandial nausea.
Porcelain Gallbladder (PGB) originally refers to the bluish discoloration and brittle consistency of the gallbladder wall, though the terms is now broadly applied to all the forms of gallbladder calcification. Extensive calcium deposition within the gallbladder wall imparts a fragile.
A 60 year old gentleman who presented with Obstructive jaundice secondary to periampullary carcinoma was evaluated and planned for upfront surgery. Contrast enhanced Computed tomography (CECT) scan of Thorax, abdomen and pelvis was done for staging and after ruling out metastasis.
We report a case of large atrial septal defect (ASD) in a 62-year-old female who was under regular echocardiographic follow-up on human epidermal growth factor receptor 2 (HER2) targeted treatment. She had progressive right ventricular dilatation and tricuspid regurgitation on serial echocardiograms.
Primary lymphedema is a benign condition resulting from malformations in the lymphatic vessels or nodes, which may include aplasia, hypoplasia, or hyperplasia of the lymphatic system. It is classified into three types based on the age of onset.
Streptococcus pyogenes (Group A Streptococcus, GAS) is most commonly associated with pharyngitis and scarlet fever. However, although rare, GAS may also be implicated in acute otitis media (AOM) [1] and can act as the primary site triggering systemic toxigenic complications such as scarlet fever [2].
Vasa previa is an uncommon obstetric condition characterized by unprotected fetal vessels traversing the fetal membranes, located within 2 cm of the internal cervical os, anterior to the fetal presenting part. The lack of Wharton’s jelly or placental tissue coverage predisposes these vessels to rupture during labor or membrane rupture, with dire fetal outcomes.
85 F with history of diabetes mellitus, hypertension, coronary artery disease status post percutaneous, came in for witnessed syncopal event by her daughter. Vitals were within normal limits. EKG revealed sinus rhythm with frequent PVC. Ct head showed volume loss secondary to microangiopathic disease with this pattern.
Pancreatic cysts are quite frequent, and are usually incidentally diagnosed, their management depends on the type, potential malignancy, size, location, clinical and biological consequences of the tumor. In this report, we review a number of cases involving cystic tumors of the pancreas and how they were treated in our Department of Visceral Surgery 1 at the Mohamed V Military Training Hospital in Rabat, Morocco.
Corneal opacity CO is estimated to be the cause of 5.1% of all cases of blindness and is among the top 5 causes of blindness worldwide. The lifetime burden of corneal blindness is significant because it tends to affect younger people compared with other conditions such as cataract and glaucoma.
A 94-year-old male with a history of benign prostatic hyperplasia, treated with transurethral resection of the prostate (TURP) five years ago, presented with acute left pelvic pain and inability to walk. Clinical suspicion include possible bone metastasis.
Stress induced cardiomyopathy presents as acute heart failure syndrome often related to preceding emotional or physical stressful events. This condition is reversible and considered benign although in some cases the event can be severe developing complications such shock, arrhythmias and death [1].
Primary malignant melanoma of the colon is an exceedingly rare clinical entity, accounting for less than 1% of all gastrointestinal melanomas. Its diagnosis is challenging due to nonspecific symptoms and the need to exclude more common metastatic disease.
We present a rare case of invasive hydatidiform mole (IHM) in a 52-year-old woman with persistent vaginal bleeding and elevated β-hCG following evacuation of a complete hydatidiform mole. Imaging revealed a large uterine lesion with myometrial invasion.
Post-Mastectomy Radiation Therapy (PMRT) in patients with silicone breast implants presents challenges regarding implant integrity. Hence, it is important to examine the implications of treating implants as organs at risk (OARs).
A male patient underwent right hepatectomy and portal vein reconstruction for suspected right hepatic duct cholangiocarcinoma. Post operatively, patient developed recurrent episodes of abdominal sepsis alongside a persistent bile leak. After several months of unsuccessful conservative management.
We present a case of a 32-year-old postpartum woman with status asthmaticus complicated by bilateral upper lobe collapse and pneumothoraxes. Imaging revealed bilateral upper lobe mucus plugging and barotrauma likely resulting from BiPAP use. She improved with conservative management.
Endobronchial lesions and post-obstructive pneumonia: The value of timely bronchoscopic intervention
Post-obstructive pneumonia is a known consequence of proximal airway obstruction, but the underlying causes may range from infection and mucus plugging to occult malignancy or foreign body aspiration. We present three patients with varied clinical presentations and underlying pathologies.
A 48-year-old male with a previous history of pulmonary tuberculosis presented with chronic lower urinary tract symptoms (LUTS) including dysuria, increased frequency, and bilateral flank discomfort for over two years. He had completed a full 8 month course of anti-tubercular therapy. MTB-DNA was detected via PCR.
We present a patient with hematoma formation secondary to anticoagulation therapy for upper extremity thromboses following implant-based breast reconstruction. This case illustrates that first-line ultrasound has limited utility in diagnosis when used on a breast with an implant, and cross-sectional imaging must be completed if high clinical suspicion is present.
Chediak Higashi Syndrome (CHS) is a rare inherited lysosomal storage disorder of childhood and commonly presents in the first decade of life. The hyper-inflammatory accelerated phase of the disease commonly known as Hemophagocytic Lymph histiocytosis (HLH) develops in around 85% of patients and is fatal without immediate bone marrow transplantation.
Cardiac metastasis is rare. A 42-years-old nursing officer was a known case of osteosarcoma proximal tibia diagnosed one year ago; treated with curettage and chemotherapy. He had bilateral pedal oedema with exertional dyspnea for one month due to Doxorubicin induced cardio- depressant effect causing heart failure.
Polypharmacy represents a significant and escalating public health concern, particularly within the geriatric population. It is commonly identified as the concurrent use of five or more medications daily, although definitions vary, including a range from 2 to 11 medications per day.
A pseudoaneurysm is caused by a disruption to the continuity of the arterial wall, which can be triggered by inflammation, trauma or iatrogenic factors, such as surgery, percutaneous biopsy or drainage. Here, we present the case of an eight-year-old patient who presented with progressive enlargement of an occipital swelling following head trauma involving an occipital point of impact.
Pancreatic mucinous cystadenocarcinoma (MCAC) is extremely rare predominantly occurs in women between 5th and 6th decades; the majority arises from pre-existing mucinous cystadenoma. Commonly diagnosed incidentally during investigation for often unrelated and nonspecific abdominal complaints using state-of-the art abdominal imaging.
Dentinogenic Ghost Cell Tumour (DGCT) is a rare, locally invasive, solid neoplastic variant of the Calcifying Odontogenic Cyst (COC). It accounts for 2% to 14% of all COCs. In this present report, we discuss a case of a 30-year-old female patient.
Meningioma, a benign tumor arising from arachnoid cells, rarely affects the middle ear (ME) and can either occur solitarily or as a lateral extension of a CPA meningioma. Though benign, these tumors may lead to symptoms like hearing loss, vertigo, tinnitus, and facial numbness due to cranial nerve involvement.
Voice‑related biomarkers have the attention of clinicians and data scientists because they promise objective, low‑cost insights into laryngeal and systemic health. We aimed to combine contemporary evidence, emphasizing methodological quality, regulatory readiness, and the strategic priorities
Acute neonatal dacryocystitis (AND) is a common ocular emergency in neonates, often associated with dacryocystocele. It typically presents with inflammatory swelling in the medial canthal region and can lead to serious complications if untreated.
A 62-year-old female, a known case of carcinoma tongue on chemotherapy with a longstanding tracheostomy (for the past 2 years), presented following accidental intratracheal breakage of a tracheostomy brush during routine care.
The short- and long-term implications following COVID-19 remain unclear. This case report includes a unique case of COVID-19 which was followed with the development of recurrent, widespread thrombosis.
Heterotopic tissue in the gastrointestinal tract is rare, with pancreatic and gastric heterotopia being the most reported types [1]. Heterotopic respiratory mucosa (HRM), particularly in the rectum, is exceedingly rare, with only three cases documented in the literature [2-4].
Pediatric renal tumors are uncommon, with Wilms tumor (WT) being the most frequently diagnosed. Among its subtypes, Botryoid Wilms tumor (BWT) is a rare variant distinguished by its multilobular architecture.
Hemoglobin C (HbC) is a variant that is formed as a result of missense mutation in the coding region of HBB gene. Co-inheritance of hemoglobin C and Beta thalassemia mutations results in Hb C/ Beta thalassemia, a rare hemoglobinopathy.