Latest Articles

Volume-5, 2024
Issue 11 (November)



An interesting case of anti-GAD65 encephalitis

We present the case of an 18 year old female who presented with short term amnesia, palpitations and headaches with no significant past medical history. Examination revealed inability to recall three objects, autonomic dysfunction and no focal neurological deficit.

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Salmonella meningitis: Five cases

Although salmonellosis is very common in Morocco, its involvement in purulent meningitis remains possible, although very rare. The aim of this work is to study the clinical and paraclinical epidemiological profile as well as the evolution of purulent salmonella meningitis in our department from January 2012 to December 2023 at the Mohammed VI University Hospital in the pediatrics department A in Marrakech.

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Lung herniation - A rare cause of chest pain

Lung hernias are a rare entity that results from the protrusion of part of the lung parenchyma through the rib cage. It can occur after trauma or as a post-surgical iatrogenic, but is even less common when it occurs spontaneously.

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A typical gastrointestinal metastasis of melanoma

A 74-year-old woman with a history of Charcot-Marie-Tooth type 1 neuropathy and malignant melanoma (TxN3bM0), diagnosed in 2023 and previously treated with pembrolizumab, presented to the emergency department with acute-on-chronic anemia (2 g/dL hemoglobin drop), heart failure, abdominal pain, hypotension, and melena.

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Irvan syndrome: A case report and literature review

Idiopathic Retinal Vasculitis, Aneurysms, and Neuroretinitis syndrome (IRVAN) is a rare disorder of unknown etiology. It is most commonly characterized by bilateral involvement with arterial bifurcation aneurysms, arterial vasculitis, exudative maculopathy, neuroretinitis, and peripheral retinal ischemia.

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Nailing the chest pain

A 64-year-old male with known HFrEF, hypertension and non-compaction cardiomyopathy presented for evaluation of chest pain and underwent an outpatient nuclear stress test. This showed a moderate to large, fixed, inferior apical defect and a stress LVEF of 17% which was similar to prior echocardiograms.

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Galeazzi equivalent fracture in children: A case report

Fractures of the forearm are frequently observed in children and adolescents. Among these, the Galeazzi fracture-characterized by a fracture of the radial shaft accompanied by Dislocation of the Distal Radioulnar Joint (DRUJ)-is relatively uncommon in this age group. The Galeazzi equivalent fracture is a variation that presents in pediatric populations as a radius fracture associated with a displaced physeal injury of the distal ulna, but without DRUJ dislocation.

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Rapid evolution of delayed pericardial tamponade following cardiac surgery: Clinical image

Delayed pericardial tamponade represents a rare but life-threatening complication following cardiac surgery. We present a case of a 67-year-old male who developed delayed pericardial tamponade on postoperative day 8 following a Bio-Bentall procedure with diagnosis confirmed via bedside transthoracic echo facilitating expeditious operative intervention and safe hospital discharge.

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A young lady with painful fingers and abnormal fundus

A 36 years old previously healthy lady presented with painful 2nd and 5th fingers of both hands for 6 months duration. The pain had gradually got worse and was found to have blackish complexion of the fingers suggestive of gangrene. There were no joint involvements or any skin changes.

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Roadmap for drug discovery from medicinal plants

The discovery of new drugs from medicinal plants offers potential therapeutic solutions for complex diseases, leveraging bioactive compounds derived from traditional knowledge. This road map follows a systematic approach for drug development

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Cavernous sinus syndrome secondary to pituitary apoplexy

A 64-year old woman with metastatic gastric adenocarcinoma and recurrent pituitary macroadenoma presented with a one day history of headache and vomiting. She was diagnosed with small pulmonary emboli one week prior and was treated with therapeutic enoxaparin at 1 mg/kg BD.

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A patient with massive splenomegaly and its cause unfound

The most common causes of splenomegaly are liver disease, malignancy, and infection. 84% of cases with progressive splenic enlargement were associated with hematological diseases, especially malignancy. Acute infections, anemia, and splenic rupture are the most common complications of splenomegaly

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Knowledge attitude and practices related on ionizing radiation exposure of women of childbearing age or pregnant women in Cameroon

The concern about ionizing radiation exposure of women of child-bearing age or pregnant women is still relevant and CT scanning alone is a subject of interest as it is responsible for 58% of radiation exposure from medical x-rays. The objective of our survey was to evaluate the knowledge and practices of radiation protection of CT scan users in women of childbearing age in the city of Douala in Cameroon.

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Worst nightmare of chronic silicosis

Simultaneous bilateral pneumothorax is an uncommon presentation and usually occurs in the context of secondary spontaneous pneumothorax. A 45-year-old man diagnosed with complicated silicosis for, with a history of numerous pneumothorax requiring inpatient treatment, is readmitted to the hospital with a new left pneumothorax.

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Post-herpetic neuralgia: A rare clinical image

Herpes zoster (HZ) is a self-limiting condition in which the discomfort subsides with the conclusion of the vesicular eruption. However, a sizable portion of individuals may experience pain that lasts or recurs months to years after the rash has healed; this condition is known as post-herpetic neuralgia (PHN).

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Severe brucella endocarditis on native tricuspid valve with a good outcome: A case report

Brucellosis causes polymorphic symptoms. Infective Endocarditis (IE) remains an exceptional location. We report a rare case of tricuspid brucella endocarditis. A 48 year old man, with a history of psoriasis, Intravenous (IV) opiate drug addiction and regular use of raw, unpasteurized milk, presented to the emergency department for fever, myalgia and painful urination that has been going on for three weeks.

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Redefining clinical expectations: A rare case report of toxic epidermal necrolysis in a glioblastoma patient undergoing concurrent temozolomide and cranial irradiation

Temozolomide (TMZ), an alkylating agent derived from dacarbazine, is approved for treating Glioblastoma Multiforme (GBM), an aggressive Central Nervous System (CNS) tumour. It is usually administered with radiation therapy after tumour surgery or as adjuvant chemotherapy. While TMZ demonstrates significant clinical efficacy, it is associated with its own toxicity profile and side effects, including leukopenia, thrombocytopenia, hepatotoxicity, nausea, constipation, and fatigue.

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Enigma of sudden onset seizures: Streptococcus pneumoniae and herpes simplex virus-1 central nervous system co-infection: A rare event

Herpes Simplex Virus-1 (HSV-1) encephalitis and Streptococcus pneumoniae meningitis co-infection is an exceptionally rare but clinically significant condition that raises distinct diagnostic and therapeutic issues. S. pneumoniae is the principal cause of bacterial meningitis, while HSV-1 is the most common cause of viral encephalitis in adults. Although they have different causes, co-infections can happen, commonly complicating the clinical situation and delaying diagnosis.

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