Subject Articles


Restricted diffusion in the corpus callosum: Marchiafava-Bignami disease

Marchiafava-Bignami disease (MBD) is a very rare demyelinating/ necrotic disorder of the corpus callosum and nearby subcortical white matter, seen mostly in chronic alcoholics. We present here the magnetic resonance imaging findings of Machiafava-Bignami disease in a 75-year-old man with a history of untreated diabetes mellitus who presented with a sudden onset of alteration in speech and multiple falls in a few days.