Articles

Volume-5, 2024
Issue 11 (November)



Is there link between chronic allergic fungal rhinosinusitis and Alpha-1 antitrypsin deficiency? A case report

Diagnosis of AAT deficiency starts with clinical suspicion and it is confirmed through serum levels and phenotyping/genotyping. AAT deficiency represents a potential contributing factor to chronic allergic fungal rhinosinusitis. We report a case of chronic fungal allergic rhinosinusitis associated with alpha-1 antitrypsin deficit.

PDF HTML

Recurrent type II second branchial cleft cyst: A case report

We present a compelling case of a 29-year-old gentleman who developed a progressively enlarging, painless lump on the left side of his neck. MRI imaging was instrumental in confirming the size and location of the mass. Surgical excision remains the mainstay of treatment in such cases.

PDF HTML

Diabetic ketoacidosis with intra-abdominal hernia: A rare cause of small bowel perforation - A case report

Diabetic Ketoacidosis (DKA) is a lifethreatening medical condition. Intra-abdominal hernia causes intestinal obstruction that results in a severe acute abdomen; if it is not diagnosed and treated in time, it can result in serious complications such as intestinal strangulation necrosis, intestinal perforation, and even septic shock, resulting in death.

PDF HTML

The fortuitous discovery of bilateral retinal coloboma

Colobomas are congenital malformations due to an abnormality in the closure of the colobomic cleft during embryonic life, which can affect various ocular structures such as the retina. We report the case of a 50-year-old female patient with no previous history of the condition, who presented for a change of optical correction.

PDF HTML

Salmonella meningitis: Five cases

Although salmonellosis is very common in Morocco, its involvement in purulent meningitis remains possible, although very rare. The aim of this work is to study the clinical and paraclinical epidemiological profile as well as the evolution of purulent salmonella meningitis in our department from January 2012 to December 2023.

PDF HTML

Lung herniation - A rare cause of chest pain

Lung hernias are a rare entity that results from the protrusion of part of the lung parenchyma through the rib cage. It can occur after trauma or as a post-surgical iatrogenic, but is even less common when it occurs spontaneously.

PDF HTML

A typical gastrointestinal metastasis of melanoma

A 74-year-old woman with a history of Charcot-Marie-Tooth type 1 neuropathy and malignant melanoma (TxN3bM0), diagnosed in 2023 and previously treated with pembrolizumab, presented to the emergency department with acute-on-chronic anemia (2 g/dL hemoglobin drop), heart failure, abdominal pain, hypotension, and melena.

PDF HTML

Irvan syndrome: A case report and literature review

Idiopathic Retinal Vasculitis, Aneurysms, and Neuroretinitis syndrome (IRVAN) is a rare disorder of unknown etiology. It is most commonly characterized by bilateral involvement with arterial bifurcation aneurysms, arterial vasculitis, exudative maculopathy, neuroretinitis, and peripheral retinal ischemia.

PDF HTML

Nailing the chest pain

A 64-year-old male with known HFrEF, hypertension and non-compaction cardiomyopathy presented for evaluation of chest pain and underwent an outpatient nuclear stress test. This showed a moderate to large, fixed, inferior apical defect and a stress LVEF of 17% which was similar to prior echocardiograms.

PDF HTML

Galeazzi equivalent fracture in children: A case report

Fractures of the forearm are frequently observed in children and adolescents. Among these, the Galeazzi fracture-characterized by a fracture of the radial shaft accompanied by Dislocation of the Distal Radioulnar Joint (DRUJ)-is relatively uncommon in this age group.

PDF HTML

Rapid evolution of delayed pericardial tamponade following cardiac surgery: Clinical image

Delayed pericardial tamponade represents a rare but life-threatening complication following cardiac surgery. We present a case of a 67-year-old male who developed delayed pericardial tamponade on postoperative day 8 following a Bio-Bentall procedure with diagnosis confirmed via bedside transthoracic echo facilitating expeditious operative intervention and safe hospital discharge.

PDF HTML

A young lady with painful fingers and abnormal fundus

A 36 years old previously healthy lady presented with painful 2nd and 5th fingers of both hands for 6 months duration. The pain had gradually got worse and was found to have blackish complexion of the fingers suggestive of gangrene. There were no joint involvements or any skin changes.

PDF HTML

Acute liver injury and pulmonary embolism secondary to nitrous oxide inhalation: A case report

Nitrous oxide is an inhalational anesthetic with a high abuse potential. Its increased abuse in recent times has been associated with adverse effects of myeloneuropathy, venous thrombosis, myocardial infarction, and pneumothorax. We report a case of a 36-year-old male who presented with acute onset chest pain following inhalation of nitrous oxide.

PDF HTML

Roadmap for drug discovery from medicinal plants

The discovery of new drugs from medicinal plants offers potential therapeutic solutions for complex diseases, leveraging bioactive compounds derived from traditional knowledge. This road map follows a systematic approach for drug development, starting from the collection and authentication of medicinal plants

PDF HTML

Cavernous sinus syndrome secondary to pituitary apoplexy

A 64-year old woman with metastatic gastric adenocarcinoma and recurrent pituitary macroadenoma presented with a one day history of headache and vomiting. She was diagnosed with small pulmonary emboli one week prior and was treated with therapeutic enoxaparin at 1 mg/kg BD.

PDF HTML

Inverted left atrial appendage during acute aortic dissection repair

Inverted Left Atrial Appendage (LAA) is an uncommon event in cardiovascular surgery. The findings on echocardiography are sometimes misled into thrombus or tumor. We experienced a case with inverted LAA during total aortic arch repair for acute aortic dissection.

PDF HTML

Spontaneous thoracic epidural hematoma presenting with delayed neurological deficits

Spontaneous Spinal Epidural Hematoma (SEH) is a rare cause of acute spinal cord compression, with an estimated incidence of 0.1 per 100,000 patients annually. This case report describes a 63-year- old male who presented with a 10-day history of severe lower back pain, right foot numbness, and right lower limb weakness

PDF HTML

A patient with massive splenomegaly and its cause unfound

The most common causes of splenomegaly are liver disease, malignancy, and infection. 84% of cases with progressive splenic enlargement were associated with hematological diseases, especially malignancy. Acute infections, anemia, and splenic rupture are the most common complications of splenomegaly

PDF HTML

Severe encephalitis complicated by intracranial hypertension and incipient uncal herniation in a 41-year-old woman: A case report

We present a case of a 41-year-old female who developed encephalitis complicated by increased intracranial pressure (HTIC) and incipient uncal herniation. The patient presented with fever, headache, and progressive loss of consciousness. Brain imaging revealed a right temporo-insular lesion with associated signs of HTIC.

PDF HTML

Knowledge attitude and practices related on ionizing radiation exposure of women of childbearing age or pregnant women in Cameroon

The concern about ionizing radiation exposure of women of child-bearing age or pregnant women is still relevant and CT scanning alone is a subject of interest as it is responsible for 58% of radiation exposure from medical x-rays. The objective of our survey was to evaluate the knowledge and practices of radiation protection of CT scan users in women of childbearing age in the city of Douala in Cameroon.

PDF HTML

A case of sacrococcygeal teratoma of a three-year children

We report a rare case of a 3-year-old boy who presented with multiple pelvi-iliac masses and a mixed tissular and cystic retrosacrococcygean mass. The diagnosis was confirmed by Computed Tomography (CT) scan and Magnetic Resonance Imaging (MRI).

PDF HTML

A case of Iga MGUS associated leukocytoclastic vasculitis resolved with chemotherapy

Monoclonal Gammopathy of Undetermined Significance (MGUS) is a common entity with prevalence increasing with age. While most cases are asymptomatic, a minority of cases may be associated with end organ damage through mechanisms outside of deposition of the monoclonal immunoglobulin or light chain produced by the culprit clonal cell population.

PDF HTML

Different social media utilization consequences on adult food behavior and mental health condition

Social media has become an integral part of our day-to-day life. Now-a days it difficult to find anyone not using social media or smart phone. The use of smart phone and social media consistently controlling our daily life style, eating pattern and emotions. Thus, the aim of our study to explore the impact of different social media scrolling on (i) changes

PDF HTML

Worst nightmare of chronic silicosis

Simultaneous bilateral pneumothorax is an uncommon presentation and usually occurs in the context of secondary spontaneous pneumothorax. A 45-year-old man diagnosed with complicated silicosis for, with a history of numerous pneumothorax requiring inpatient treatment, is readmitted to the hospital with a new left pneumothorax.

PDF HTML

Post-herpetic neuralgia: A rare clinical image

Herpes zoster (HZ) is a self-limiting condition in which the discomfort subsides with the conclusion of the vesicular eruption. However, a sizable portion of individuals may experience pain that lasts or recurs months to years after the rash has healed; this condition is known as post-herpetic neuralgia (PHN).

PDF HTML

Multi-modality cardiac imaging in an adult patient with unrepaired tetralogy of fallot

Tetralogy of Fallot (TOF) is the most common cyanotic congenital heart defect in children worldwide. Surgical correction is required in early childhood and non-operative survival past the fourth decade is rarely described. We report an interesting case demonstrating the utility of multimodality imaging, including Transthoracic Echocardiography (TTE).

PDF HTML

Severe brucella endocarditis on native tricuspid valve with a good outcome: A case report

Brucellosis causes polymorphic symptoms. Infective Endocarditis (IE) remains an exceptional location. We report a rare case of tricuspid brucella endocarditis. A 48 year old man, with a history of psoriasis, Intravenous (IV) opiate drug addiction and regular use of raw, unpasteurized milk, presented to the emergency department for fever, myalgia and painful urination that has been going on for three weeks.

PDF HTML

Redefining clinical expectations: A rare case report of toxic epidermal necrolysis in a glioblastoma patient undergoing concurrent temozolomide and cranial irradiation

Temozolomide (TMZ), an alkylating agent derived from dacarbazine, is approved for treating Glioblastoma Multiforme (GBM), an aggressive Central Nervous System (CNS) tumour. It is usually administered with radiation therapy after tumour surgery or as adjuvant chemotherapy. While TMZ demonstrates significant clinical efficacy, it is associated with its own toxicity profile and side effects, including leukopenia, thrombocytopenia, hepatotoxicity, nausea, constipation, and fatigue.

PDF HTML

Enigma of sudden onset seizures: Streptococcus pneumoniae and herpes simplex virus-1 central nervous system co-infection: A rare event

Herpes Simplex Virus-1 (HSV-1) encephalitis and Streptococcus pneumoniae meningitis co-infection is an exceptionally rare but clinically significant condition that raises distinct diagnostic and therapeutic issues. S. pneumoniae is the principal cause of bacterial meningitis, while HSV-1 is the most common cause of viral encephalitis in adults. Although they have different causes, co-infections can happen, commonly complicating the clinical situation and delaying diagnosis.

PDF HTML